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Mounjaro is a highly effective weight loss treatment, shown in clinical trials to help achieve ~20% body weight loss. It is the latest GLP1 weight loss injection, and is used for people with a body mass index (BMI) over 30.
It contains the drug tirzepatide
It is known as Zepbound in the US, but is launching in the UK under the brand name Mounjaro.
It is injected ONCE weekly under the skin.
How does it work?
Mounjaro contains the active ingredient tirzepatide. Tirzepatide is from a class of drugs called GLP-1 agonists. This is a class of drug which helps regulate hunger and is released by the intestines after a meal.
Due to being similar to GLP-1, Mounjaro regulates appetite causing you to feel fuller and less hungry. This can lead to eating fewer calories and losing weight. Focussing on eating a reduced-calorie diet will further enhance the benefits of Mounjaro.
It also helps prevent excess sugar being converted into fat, reducing fat storage in the body
Is it for me?
Mounjaro should only be used to help with weight loss if you have already tried and failed to lose weight through exercise and diet alone, however there are other GLP-1 drugs which are availble. These incude Saxenda, Wegovy and Ozempic.
Mounjaro can be used for patients who have a BMI of over 30, or in patients with a BMI over 27, and other risk factors such as;
- Diabetes type 2
- High cholesterol
- Obstructive sleep apnoea
- High blood pressure
How effective is it?
When using Mounjaro pens to suppress appetite, you can expect to lose a around 15-20% of your initial body weight after completing treatment. This is the most effective of all the released GLP-1 medications so far.
These figures have been achieved by patients who have maintained on the highest strength of Mounjaro, which is the 15mg strength.
Patients who maintain at 10mg, lose on average of 19%, while patients who maintain at 15mg, can lose around 15%.
The lower strengths of Mounjaro 2.5 and 5mg will not achieve best results. While some weight loss will be observed, the primary function of these doses is to help your body adjust to the drug without experiencing serious side effects.
Dosage
Weeks | Dose | Notes |
---|---|---|
1-4 | 2.5 mg once weekly | Initial dose for titration |
5-8 | 5 mg once weekly | Assess tolerance before increase |
9-12 | 7.5 mg once weekly | Assess tolerance before increase |
13-16 | 10 mg once weekly | Monitor for efficacy and tolerability |
17-20 | 12.5 mg once weekly | Further increase based on clinical response |
21 onwards | 15 mg once weekly | Maintenance dose if well tolerated |
Prices
Dosage | Price | Discount Price per Pen |
---|---|---|
1 Pen 2.5mg | $170 | |
1 Pen 5mg | $200 | |
1 Pen 7.5mg | $240 | |
1 Pen 10mg | $240 | |
1 Pen 12.5mg | $285 | |
1 Pen 15mg | $285 | |
2 Pens 2.5mg + 5mg | $360 | $170/pen |
2 Pens 10mg | $526 | $250/pen |
3 Pens 10mg | $774 | $243/pen |
2 Pens 15mg | $550 | $270/pen |
Side effects
The most common side effects with Mounjaro affect the digestive system. These can include things like nausea, vomiting, diarrhoea and constipation. Most patients should see these effects subside after a few days.
Other common side effects include:
- Feeling weak or tired
- Dizziness
- Insomnia
- Injection site reactions such as bruising, pain or a rash
The dosage titration of the drug, is designed to minimise side effects. Strating with Mounjaro 2.5mg, and moving up through 5mg in 2.5mg increments, helps the body adjust to the drugs impact. Doing this gradual titration, will allow you to minimise side effects and get the most out of your treatment.
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